Advantra Z™ triggers beta-3 receptors.
The key to Advantra Z™ is its ability to stimulate beta-3 cell receptors with minimal impact on alpha-1, alpha-2, beta-1, and beta-2 receptors. This means that Advantra Z™ functions to increase the metabolic rate without affecting heart rate or blood pressure.
Advantra Z™'s unique composition of adrenergic amines causes the release of adrenaline and nonadrenaline – most likely, in the vicinity of the beta-3 receptor sites which are found primarily in adipose tissue and the liver.
Stimulation of these beta-3 receptors elicits the breakdown of fat – known as lipolysis. Simulataneously, this stimulation causes an increase in the metabolic rate – thermogenesis – which burns calories.
How cell receptors respond to adrenergic amines.
Every cell in the body has cell receptors – called alpha-1 and -2 and beta-1, -2, and -3 – that can be occupied by the body's own adrenergic amines: adrenaline and nonadrenaline.
When a receptor is occupied, the amine elicits a response from the cell. But how that response is perceived by the body depends on the type of receptor, the number and predominant types of receptors found on the cell, and the tissue or organ containing the cell.
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While the body's overall response to adrenergic amines is complex, in general:
